Description of SAMe 400mg (SAM-e) Enteric Coated 30 tabs from Source Naturals
SAM-e - S-Adenosyl-L-Methionine 200 mg and 400 mg
Supports Joint Comfort, Function and Mobility
SAM-e (SAMe) is a stable, bioavailable form of S-adenosyl-L-methionine. These
tablets are enteric coated and blister packed to prevent breakdown and inactivation
of the ingredients. Dozens of clinical studies have demonstrated that SAM-e
supports joint comfort, function and mobility in the spine, hips and knees.
It is important to the joints because of its critical role in cartilage formation.
Studies also show that SAM-e helps support a positive outlook. It is able to
cross the blood-brain barrier where it affects the synthesis and activation
of various proteins, such as neurotransmitters. SAM-e is known as a "methyl
donor." This means that it works by giving up a piece of itself (a methyl
group consisting of one carbon and three hydrogen atoms) to other molecules.
Methylation plays a part in many critical cellular functions. SAM-e is present
in every living cell in the body. However, levels of SAM-e tend to decline with
SAM-e - A Multipurpose Nutrient
SAM-e, or S-adenosyl L-methionine, is formed when our bodies combine the amino
acid L-methionine with ATP, the primary energy-carrying molecule in our cells.
SAM-e is a multipurpose nutrient, which is present in every living cell.
Because SAM-e is involved in so many vital processes, it is important that our
bodies produce sufficient SAM-e. However, SAM-e levels tend to decline with
age, and also can be affected by dietary imbalances. To produce adequate amounts,
we need to consume not only methionine-containing protein foods, but also foods
rich in vitamins B-6, B-12 and folic acid, which are needed to ensure the synthesis
SAM-e also is a highly unstable molecule. A lot of scientific research was needed
to make it available as a supplement. Source Naturals has studied the research
and offers this vital nutrient in a form your body can use.
Methylation is the Key
SAM-e is known as a "methyl donor". This means that it works by giving
up a piece of itself (a methyl group consisting of one carbon and three hydrogen
atoms) to other molecules. This methylation process affects the synthesis, activation
and metabolism of various hormones, neurotransmitters, phospholipids, nucleic
acids, proteins and other biological molecules. Methylation plays a part in
many critical functions, including the maintenance of cell membranes, the removal
of toxic substances from the body and the production of mood-boosting neurotransmitters
such as dopamine and serotonin.
SAM-e - Effective Joint Support
SAM-e has been used in Europe for two decades for joint support. Dozens of clinical
studies have demonstrated that SAM-e supports joint comfort, function and mobility
in the spine, hips and knees. SAM-e is important in a process called transsulfuration.
The breakdown of SAM-e generates sulfate groups that help maintain joint cartilage.
SAM-e helps to form proteoglycans, which are used to renew the matrix of cartilage.
SAM-e Promotes Mental Well-Being
Studies also show that SAM-e helps support a positive outlook. Although the
mechanism by which SAM-e promotes mental well-being is not known, we do know
it is able to cross the blood-brain barrier, where it affects the production
of mood-boosting neurotransmitters.
Supplement Facts for 400 mg
Serving Size: 1 tablet
SAM-e (S-adenosyl-L-methionine) 400 mg
from 800 mg of SAM-e disulfate tosylate
Other Ingredients: cellulose, hydroxypropyl methylcellulose phthalate, titanium
dioxide, mannitol, stearic acid, triacetin, sodium starch glycolate, modified
cellulose gum, citric acid, silica, and yellow ochre.
Warning: If you are pregnant, breastfeeding or are taking antidepressant medication,
consult your physician before using SAM-e product. Take this product under medical
supervision if you have bipolar disorder. In a small percentage of people SAM-e
may cause nausea which tends to subside with long-term use.
Suggested Use: One SAM-e tablet, one to three times daily. Take SAM-e
tablets on an empty stomach.
Source Naturals SAM-e is suitable for vegetarians. Contains no yeast, dairy,
egg, gluten, soy or wheat. Contains no preservatives or artificial color, flavor
Disclaimer: The statements made, or products sold through this website, have not been evaluated by the Food and Drug Administration. They are not intended to diagnose, treat, cure, or prevent any disease. Actual results may vary significantly and are dependent on individuals. You should always consult with your physician before starting any health products or any health-related programs.